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EMBO Young Investigator

Mauro Gaya

Centre d’Immunologie, Marseille | France

YIP 2023–2026

B cell memory in barrier tissues

One of the main features of our immune system is the ability to remember previously-encountered microbes. In our lab, we study how this memory is established in barrier tissues upon infection. In particular, we study tissue-resident memory B cells, which can rapidly produce antibody-secreting cells upon encounter of pathogens in the lung/gut mucosa. Targeting these cells is a promising approach to protect against airborne or enteric pathogens.

Keywords: B cells / IgA / fate decision / long-lived plasma cells / memory B cells

Subject area(s): Immunology | Microbiology, Virology & Pathogens