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Portrait of Melissa H. Little

EMBO Member

Melissa H. Little

EMBO 2024

University of Copenhagen, Denmark

Kidney organoids from human pluripotent stem cells

Our group research is focused on analysing kidney development, and discovering potential regenerative therapies in the kidney. We generate kidney organoids from human pluripotent stem cells, which are being applied to disease modelling, drug screening and renal replacement therapies. Using fundamental developmental biology, our stem cell research illustrates the power of biological understanding for applications related to product development.

Kidney / renal failure / pluripotent stem cells / organ development / tissue patterning