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EMBO Global Investigator

Meng How Tan

Nanyang Technological University, Singapore | Singapore

GIN 2020–2024

RNA editing in development and diseases

Our lab is interested in understanding how gene expression is controlled at the RNA level, with a particular emphasis on the ADAR (Adenosine Deaminases Acting on RNA) family of enzymes. We are dissecting the physiological roles of ADARs in normal development and examining how aberrant ADAR activity can lead to human diseases. In addition, we are inventing new genomic technologies to facilitate our understanding of ADARs.

Keywords: RNA editing / RNA modifications / epitranscriptome / ADAR / genomic technologies

Subject area(s): Genomic & Computational Biology | RNA | Systems Biology