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EMBO Member

Michael H. Malim

King's College, London | United Kingdom

EMBO 2005

Molecular pathogenesis of HIV/AIDS

Our laboratory utilises molecular genetic, cultured cell, biochemical, structural, bioinformatic and cohort-based methodologies to study the biological principles that underpin HIV replication and pathogenesis (AIDS). Current areas of interest include host-virus interactions, cell-encoded mechanisms of anti-viral resistance (e.g., the APOBEC3 and MX proteins) and virus particle assembly.

Keywords: HIV / AIDS / molecular pathogenesis / innate immunity / nucleic acid metabolism / virus assembly

Subject area(s): Microbiology, Virology & Pathogens | Molecular Medicine | RNA