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EMBO Young Investigator

Michael Potente

MPI für Herz- und Lungenforschung, Bad Nauheim | Germany

YIP 2015

Regulation of angiogenesis by metabolism

Our laboratory focuses on blood vessels, particularly the regulation of blood vessel growth (angiogenesis) by metabolism. We study how endothelial cells (ECs) sense their metabolic microenvironment and how they use this information to build vessels of tissue-specific size, shape and function. We are also interested in the metabolism of ECs, aiming to understand how changes in endothelial bioenergetics impact vascular growth and homeostasis.

Keywords: Angiogenesis / metabolism / cancer / cardiovascular disease / endothelial cells / signal transduction

Subject area(s): Cell & Tissue Architecture | Molecular Medicine | Signal Transduction