
EMBO Associate Member
Michael R. Green
DeceasedEMBO 2010
1954 – 2023
Targetable pathways in cancer and other diseases
My laboratory is interested in understanding the molecular basis of human diseases – in particular cancer and certain rare genetic disorders – and identifying factors and regulatory pathways that can be therapeutically targeted to treat these conditions. In general our research focuses on identifying new factors and regulatory pathways that promote or prevent cancer, and modulating gene expression as a therapeutic approach.
Keywords
Cancer biology / drug resistance mechanisms / epigenetic regulation / genome-wide functional screening / rare diseases / transcriptional regulation / oncogenes / tumor suppressor genes