Search    Show all

1 People found

filters applied:


1 / 1

EMBO Member

Michael S. Neuberger

1953 – 2013

EMBO 1989 | CouC 90–95

Antibody gene diversification

The research of myself and my colleagues primarily focusses on molecular mechanism of antibody gene diversification (immunoglobulin somatic hypermutaion and class-switch recombination) and extends into the wider contribution of enzyme-catalysed DNA deamination by AID/APOBEC proteins to genome instability and viral restriction. We are also interested in exploiting the antibody iterative maturation process for antibody/protein engineering purposes.

Subject area(s): Genome Stability & Dynamics | Immunology