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EMBO Member

Michael Sixt

Institute of Science and Technology Austria (IST), Klosterneuburg | Austria

EMBO 2014 | FelC 15–20 | YipC 21–23

Morphodynamics of immune cells

My laboratory studies the cell biology of immune cells. We currently investigate how the cytoskeleton generates force to deform the cell body, how this force is transduced to the extracellular environment in order to promote single cell locomotion, how the cells are polarized and guided within tissues by extracellular signaling cues and how leukocytes exchange signals in cell-cell contacts.

Keywords: Cell migration / chemotaxis / cell shape / tissue architecture / cytoskeleton

Subject area(s): Cell & Tissue Architecture | Immunology | Signal Transduction