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EMBO Member

Michel O. Steinmetz

Paul Scherrer Institut, Villigen | Switzerland

EMBO 2010 | MemC 13–16

Proteins and ligands regulating the microtubule cytoskeleton

Understanding how diverse and complex proteins come together spatially and temporally and how their specific interactions translate into cellular functions represents a major challenge in contemporary biology. Our group uses X-ray crystallography in combination with biochemical and biophysical methods to investigate dynamic protein and ligand interactions regulating the microtubule cytoskeleton.

Keywords: Microtubule cytoskeleton / protein-protein interactions / protein-ligand interactions / biochemistry / structural biology

Subject area(s): Proteins & Biochemistry | Structural Biology & Biophysics