Paul Scherrer Institut, Villigen | Switzerland
EMBO 2010 | MemC 13–16
Understanding how diverse and complex proteins come together spatially and temporally and how their specific interactions translate into cellular functions represents a major challenge in contemporary biology. Our group uses X-ray crystallography in combination with biochemical and biophysical methods to investigate dynamic protein and ligand interactions regulating the microtubule cytoskeleton.
Keywords: Microtubule cytoskeleton / protein-protein interactions / protein-ligand interactions / biochemistry / structural biology