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EMBO Member

Michele De Luca

Università di Modena | Italy

EMBO 2018

Epithelial stem cells in cell and gene therapy

Our activity is focused on basic and translational research on epithelial stem cells. Basic research is focused on: culture and functional characterization of epithelial stem cells (epidermis, cornea, conjunctiva, urethra and oral mucosa); study of molecular mechanisms regulating self-renewal, proliferation and differentiation of squamous epithelial stem cells; new methodologies for gene correction and gene replacement in epithelial stem cells.

Keywords: Epithelial stem cells / tissue regeneration / cell therapy / gene therapy / regenerative medicine / personalized medicine / advanced therapies

Subject area(s): Cell & Tissue Architecture | Differentiation & Death | Molecular Medicine