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EMBO Associate Member

Mina J. Bissell

Lawrence Berkeley National Laboratory, Berkeley | United States

EMBO 2017

Microenvironment and tissue architecture

Mina Bissell pioneered the area of the relationship between cancer genetics and 3D tissue structure. She discovered the first ECM-response element and elucidated the mechanism by which MMPs could cause genomic instability and cancer in mammary cells. She was the major force in establishing the field of microenvironmental regulation of tissue-specificity. [from]

Keywords: Breast cancer / malignant tissue / breast tumor / breast epithelial cells / extracellular matrix

Subject area(s): Cell & Tissue Architecture | Molecular Medicine | Signal Transduction