Institut Pasteur, Paris | France
EMBO 1978 | FelC 81–84 | Council 91–96
I am interested in genetic and epigentic control of gene expression during development and disease including cancer. By conditional inactivation of genes encoding for transcription factors like HNF1, JunD or the SWI/SNF chromatin remodeling complex we generated a number of mouse models for cancer, type 2 diabetes and polycystic kidney disease.
Keywords: Gene expression in eukaryotes / cell cycle control & transformation / differentiation & development