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EMBO Member

Murray Stewart

MRC LMB, Cambridge | United Kingdom

EMBO 2006

mRNA export & integration with gene expression

My research effort is focused on the nuclear export of mRNA and how it is integrated with preceding steps in the gene expression pathway. We aim to determine the structure of key proteins and complexes and use this information to engineer novel mutants that can be used to determine how function is generated by interactions between the components of the system.

Keywords: Nuclear trafficking / cell motility / structural biology / X-ray crystallography / integrating nuclear RNA processing with export

Subject area(s): Membranes & Transport | Proteins & Biochemistry | Structural Biology & Biophysics