Translational control in health and disease
My group is conducting research on the mechanism and control of translation initiation in eukaryotes in health and disease. We are investigating the role that translational control plays in development, learning and memory and microRNA function, and the dysregulation of translation in cancer, autism, neurodegenerative disease and virus infections. We focus on signaling pathways, such as PI3K/Akt/mTOR that control translation rates.
Keywords
mRNA translation / mTOR pathway / learning and memory / autism / cancer / ASD / memory / circadian clock / eIF4E