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EMBO Member

Nancy E. Hynes

University of Bern | Switzerland

EMBO 1998 | PubC 09–09 | FelC 16–18

Approaches to inhibit breast cancer metastasis

My lab works on signaling proteins and pathways involved in breast cancer growth and metastasis. In our work, we use ex vivo and in vivo models of metastatic breast cancer. We study the effects of inhibitors, both targeted and standard chemotherapeutics, on tumors and metastasis. We also delineate the pathways and proteins that contribute to cancer therapy resistance, primary and acquired.

Keywords: Breast cancer / mammary gland development / ErbB family of receptor tyrosine kinases / cell motility / FGF receptors

Subject area(s): Development | Molecular Medicine | Signal Transduction