
EMBO Associate Member
Nick Barker
EMBO 2022
Institute of Molecular and Cell Biology (IMCB), Singapore, Singapore
Epithelial stem cells and cancer
My group employs mouse models and organoid technologies to identify and characterise stem cell populations and their local niches responsible for tissue maintenance, repair and cancer initiation/progression. This research is expected to accelerate efforts to safely exploit adult stem cells for regenerative medicine applications and deliver more effective cancer therapies in the clinic.
Keywords
Lgr5 / stem cells / cancer stem cells / gastric cancer / colon cancer