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EMBO Associate Member

Nick Barker

Institute of Molecular and Cell Biology (IMCB), Singapore | Singapore

EMBO 2022

Epithelial stem cells and cancer

My group employs mouse models and organoid technologies to identify and characterise stem cell populations and their local niches responsible for tissue maintenance, repair and cancer initiation/progression. This research is expected to accelerate efforts to safely exploit adult stem cells for regenerative medicine applications and deliver more effective cancer therapies in the clinic.

Keywords: Lgr5 / stem cells / cancer stem cells / gastric cancer / colon cancer

Subject area(s): Development | Differentiation & Death | Molecular Medicine | Signal Transduction