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EMBO Member

Nick Brown

University of Cambridge | United Kingdom

EMBO 2010

Molecular mechanisms of morphogenesis

We study how cell adhesion and the cytoskeleton are integrated in morphogenesis. Our main focus is on the intracellular pathways induced by integrin adhesion to the extracellular matrix, using the diverse functions of integrins in Drosophila development as assays for molecular function. Our Cambridge subgroup of FlyBase curates genetic and gene function data from the research literature.

Keywords: Integrins / Drosophila / cytoskeleton / cell adhesion / extracellular matrix / FlyBase

Subject area(s): Cell & Tissue Architecture | Development | Systems Biology