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EMBO Young Investigator

Nicolas Plachta

Institute of Molecular and Cell Biology (IMCB), Singapore | Singapore

YIP 2016

Imaging mammalian development

Our goal is to reveal how mammalian cells resolve their fate, shape and position in the body in real time. To achieve this, we combine imaging and quantitative methods to study cells directly in the living mouse embryo. We recently showed how transcription factors bind DNA to control cell fate in the embryo. We also used imaging to show how cells form tissue-like structures and how mechanical forces shape the early embryo.

Keywords: Mouse embryo / transcription / cell dynamics / imaging / differentiation

Subject area(s): Cell & Tissue Architecture | Chromatin & Transcription | Development