Francis Crick Institute, London | United Kingdom
We study how tissue growth is regulated during development and adult life. We are particularly interested in the Hippo signalling pathway, which senses diverse cues such as tissue architecture and nutrient/energy availability. We use a large array of methods, from Drosophila and mouse genetics, live imaging, through to proteomics, structural biology and mathematical modelling.
Keywords: Growth control / Hippo signalling / Drosophila / development / mechanotransduction