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EMBO Member

Nicolas Tapon

Francis Crick Institute, London | United Kingdom

EMBO 2018 | CouC 20–22 | EEsC 22– | CouC 23–25

Control of tissue growth and architecture

We study how tissue growth is regulated during development and adult life. We are particularly interested in the Hippo signalling pathway, which senses diverse cues such as tissue architecture and nutrient/energy availability. We use a large array of methods, from Drosophila and mouse genetics, live imaging, through to proteomics, structural biology and mathematical modelling.

Keywords: Growth control / Hippo signalling / Drosophila / development / mechanotransduction

Subject area(s): Cell & Tissue Architecture | Development | Signal Transduction | Systems Biology