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EMBO Young Investigator

Nina Cabezas-Wallscheid

MPI für Immunbiologie und Epigenetik, Freiburg | Germany

YIP 2022–2026

Regulation of hematopoietic stem cell dormancy

Our lab aims to provide in-depth insight into the functional signaling networks that regulate mouse and human hematopoietic stem cells (HSCs), while also pioneering therapeutic avenues for nutritional and hematological diseases. Specifically, we aim to delineate how HSCs are metabolically and epigenetically regulated by distinct dietary habits, and whether dormant HSCs exist in humans and what the biological role of the state of dormancy is.

Keywords: Hematopoietic stem cells / hematopoiesis / leukemia / diets / metabolism / epigenetics / aging

Subject area(s): Cellular Metabolism | Development | Differentiation & Death | Systems Biology