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EMBO Member

Nina Cabezas-Wallscheid

ETH, Zurich | Switzerland

EMBO 2026

Blood stem cell regulation in ageing and disease

Our lab investigates how hematopoietic stem cell (HSC) dormancy is regulated during homeostasis, ageing, and hematological diseases. Using genetic models, dietary interventions, primary human samples, and single-cell multi-omics approaches, we study the metabolic and epigenetic mechanisms that preserve blood stem cell function across the lifespan and identify strategies for human healthy ageing and treatment of blood disorders.

Keywords: Hematopoietic stem cells / inflammation / leukemia / diets / metabolism / epigenetics / ageing

Subject area(s): Cellular Metabolism | Differentiation & Death | Molecular Medicine

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