Structure, function and motility of kinesins
Our laboratory studies the structure, function and mechanism of motility of kinesin superfamily molecular motors,KIFs, using molecular cell biology, molecular genetics, and structural biology combined with biophysics. Main focus is on the mechanism of intracellular transport, while molecular genetics reveals unexpected important functions of KIFs in higher brain function, brain development, brain wiring, and development of our body.
Keywords
Kinesin superfamily proteins / microtubules / intracellular transport / neurons / cytoskeleton / cell morphogenesis