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Portrait of Noel F. Lowndes

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Noel F. Lowndes

EMBO 2003 | YipC 08–12 | GinC 19–22

National University of Ireland, Galway, Ireland

Mechanisms of genome stability in human cells

We are interested in the maintenance of the integrity of the human genome, with a particular focus on newly identified partners of the central regulators of genome stability, ATM and ATR, as well as 53BP1, a regulator of DSB repair. Our work identifies novel mechanisms of relevance to tumour suppression with likely impact in diagnoses and therapeutic interventions in oncology.

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Sensing DNA damage / DNA repair / cell cycle regulation / biochemistry of checkpoint proteins / cancer biology

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ORCID profile ↗Noel F. Lowndes on EMBO’s Science Map