Instituto de Biología Molecular de Barcelona (IBMB), Barcelona | Spain
EMBO 2008 | CouC 15–18
We study structure-function relationships of proteins and macromolecular complexes involved in pathological processes, in particular virus particles, viral proteins and protein-complexes involved in RNA replication as well as other large assemblies. We use a number of molecular and structural biology techniques, in particular X-ray crystallography and combinations of X-ray crystallography and cryo-electron microscopy.
Keywords: X-ray crystallography / macromolecular complexes / vault particle / viral particles / RNA virus-complexes / RNA-virus replication / antiviral strategies
Subject area(s): Microbiology, Virology & Pathogens | Proteins & Biochemistry | Structural Biology & Biophysics