EMBO Member
Cancer Research UK Scotland Institute, Glasgow | United Kingdom
EMBO 2024
Our group examines the molecular mechanisms underpinning colorectal cancer initiation, progression, response to therapy, and metastasis. To this end, we use state-of-the-art preclinical models harbouring key driver mutations. Our overarching goals are to identify early-stage diagnostic biomarkers and develop stage- and subtype-specific targeted therapies.
Keywords: Adenomatous Polyposis Coli / colorectal cancer / MTOR / neutrophils / models of disease / stem cell competition / intestine
Subject area(s): Differentiation & Death | Molecular Medicine | Signal Transduction