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EMBO Member

Özlem Keskin

Koç University, Istanbul | Türkiye

EMBO 2023

Structural modeling of protein interactions

Our work focuses on computational biology and structural bioinformatics, in particular on (i) understanding the physical principles of protein-protein interactions and modeling structural interactome and microbiome; (ii) extracting biologically relevant information from large databases, such as reconstructing protein-protein interface datasets, predicting hot spots and hot regions in protein interfaces; and (iii) understanding the molecular mechanisms of protein function by investigating protein dynamics.

Keywords: Computational modeling / protein-protein interactions / hot spots at interfaces / protein dynamics / signaling networks / bioinformatics / structure-based predictions / structural interactome

Subject area(s): Genomic & Computational Biology | Proteins & Biochemistry | Structural Biology & Biophysics | Systems Biology