EMBO Member

Paolo Lusso

NIH, Bethesda | United States

EMBO 2004

HIV-1/AIDS pathogenesis, therapy and vaccine

A major focus of my research is to study the pathogenesis of viral diseases, particularly HIV-1/AIDS, and devise innovative therapy and vaccine strategies. Primary interests include the structure-function relationships of the HIV-1 envelope, aimed at the rational design of effective vaccine immunogens, and the role and mechanism of action of endogenous antiviral factors, especially chemokines, that can influence the course of HIV-1 disease.

Keywords: Molecular virology / pathogenesis / receptors / chemokines / neutralization / antibodies / vaccines / HIV / herpesvirus

Subject area(s): Immunology | Microbiology, Virology & Pathogens | Molecular Medicine