EMBO Member
Pascal Genschik
EMBO 2012 | YipC 19–22
IBMP, Strasbourg, France
Role of Ubiquitin in Cellular Regulation
The ubiquitin-proteasome system was discovered as a central player for rapid and selective proteolysis of key regulatory proteins controlling a variety of cellular processes in all eukaryotes. Currently my main interests address two major domains in which ubiquitylation seem to play essential functions: (1) how stress hormones impinge on the cell cycle machinery and (2) protein turnover and its significance in RNA silencing.
Keywords
Ubiquitin / cullin RING ligases / cell cycle control / phytohormone signalling / post-transcriptional gene silencing