Institute of Cancer Research, London | United Kingdom
My lab focuses on the complex relationship between cell death and inflammation. In particular, we are investigating how ubiquitin- and ubiquitin-like messages are used in a spatial and temporal manner to modulate the cellular response to cell death and inflammation, and how this can be exploited to prevent tumour formation and treatment resistance.
Keywords: Apoptosis / necroptosis / cell death / inflammation / ubiquitin signalling / tssue plasticity / cancer
Subject area(s): Differentiation & Death | Proteins & Biochemistry | Signal Transduction