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EMBO Young Investigator

Patrick Müller

Friedrich-Miescher-Laboratorium der Max-Planck-Gesellschaft, Tübingen | Germany

YIP 2018

Systems biology of development

My lab uses a systems biology approach to analyze how signaling networks control gene expression in development and disease. We combine quantitative imaging, mathematical modeling, optogenetic manipulations, and synthetic gene regulatory networks with the goal to identify signaling mechanisms relevant for our understanding of self-organizing processes, tissue formation, and the treatment of disease states.

Keywords: Pattern formation / self-organization / signaling gradients / zebrafish / Nodal / BMP / optogenetics

Subject area(s): Development | Signal Transduction | Systems Biology