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EMBO Young Investigator

Paul Guichard

University, Geneva | Switzerland

YIP 2020–2024

Centriole architecture and function

My laboratory is focusing on deciphering the structural mechanisms governing centriole assembly in normal as well as pathological conditions. To this end, we are combining the use of cell biology methods, in-vitro reconstitution assays, cryo-microscopy / cryo-tomography, and expansion microscopy to gain decisive insights into these mechanisms.

Keywords: Centriole / cilia / microtubule / cryo-tomography / super-resolution microscopy

Subject area(s): Cell Cycle | Cell & Tissue Architecture | Structural Biology & Biophysics

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