Centriole architecture and function
My laboratory is focusing on deciphering the structural mechanisms governing centriole assembly in normal as well as pathological conditions. To this end, we are combining the use of cell biology methods, in-vitro reconstitution assays, cryo-microscopy / cryo-tomography, and expansion microscopy to gain decisive insights into these mechanisms.
Keywords
Centriole / cilia / microtubule / cryo-tomography / super-resolution microscopy