EMBO Member

Paulien Hogeweg

University, Utrecht | Netherlands

EMBO 2025

Computational models of multilevel evolution

We investigate how complex biological systems evolve and function. We use a bottom-up non-supervised individual-based computational modeling strategy. We explore the often surprising consequences of basic interactions, like the emergence of multilevel evolution in spatial systems, evolution of complex genotype-phenotype maps, biased mutations and evolution of evolvability.

Keywords: multilevel evolution / evolvability / genome structure / gene regulatory nets / genotype-phenotype-map / origin of life / spatial self-organization / theoretical biology / bioinformatics

Subject area(s): Genomic & Computational Biology | RNA | Evolution & Ecology

Links: orcid.org/0000-0003-3392-9839