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Portrait of Paulien Hogeweg

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Paulien Hogeweg

EMBO 2025

University, Utrecht, Netherlands

Computational models of multilevel evolution

We investigate how complex biological systems evolve and function. We use a bottom-up non-supervised individual-based computational modeling strategy. We explore the often surprising consequences of basic interactions, like the emergence of multilevel evolution in spatial systems, evolution of complex genotype-phenotype maps, biased mutations and evolution of evolvability.

multilevel evolution / evolvability / genome structure / gene regulatory nets / genotype-phenotype-map / origin of life / spatial self-organization / theoretical biology / bioinformatics