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EMBO Member

Peijun Zhang

University of Oxford | United Kingdom

EMBO 2024

Structural biology of host-pathogen interactions

We study the structure of human pathogens (e.g. HIV and SARS-CoV-2) and the molecular mechanisms of host-pathogen interactions in viral and bacterial infections. To this end, we develop and apply novel technologies for high-resolution cryo-electron microscopy and tomography, in situ structural biology and correlative light and electron microscopy, combining them with complementary computational, biophysical, and biochemical approaches.

Keywords: Cryo-EM / cryo-electron tomography / in-situ structural biology / HIV-1 / SARS-CoV-2 / bacterial chemotaxis / host-pathogen interactions / correlative microscopy

Subject area(s): Structural Biology & Biophysics | Signal Transduction | Microbiology, Virology & Pathogens