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EMBO Member

Peter Rehling

University Medical Center, Göttingen | Germany

EMBO 2022

Mitochondrial biogenesis and gene expression

Mitochondria fullfill key functions in cellular metabolism. In our work, we investigate the biogenesis of mitochondrial proteins and aim to understand how dysfunction in the biogensis process lead to human disorders. In this context, we investigate mechanisms of mitochondrial protein import, biogenesis of the OXPHOS system, and how mitochondrial gene expression is regulated to match cellular demands.

Keywords: Mitochondria / protein transport / translation / OXPHOS / mitochondrial disorders / biogenesis of cell organelles / assembly of protein complexes

Subject area(s): Proteins & Biochemistry | Molecular Medicine | Membranes & Transport | Cellular Metabolism