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EMBO Member

Petr Cejka

Institute for Research in Biomedicine, Bellinzona | Switzerland

EMBO 2021

Mechanism of DNA repair homologous recombination

My group is interested in the mechanisms of DNA double-strand break repair by homologous recombination. Primarily we study the first steps in the recombination pathway that involve controlled nucleolytic resection of the DNA breaks in their preparation for repair. Additionally, we are interested in the final steps of resolution of recombination intermediates, with a focus on meiotic recombination proteins.

Keywords: Biochemistry / DNA repair / homologous recombination / nucleases / helicases

Subject area(s): Genome Stability & Dynamics | Proteins & Biochemistry