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EMBO Member

Petr Svoboda

Inst. of Molecular Genetics, ASCR, Prague | Czech Republic

EMBO 2018 | CouC 21–23

Small RNAs and other things in mice and slugs

Our lab's primary research interest is understanding molecular mechanisms and biological roles of small RNA pathways in germlines of mammals and molluscs. We explore several research directions, which revolve around evolutionary adaptations and molecular details of small RNA pathway mechanisms, control of retrotransposons by small RNAs, and experimental manipulation of canonical RNAi pathway to provide antiviral defense.

Keywords: RNA interference / microRNA / piRNA / dsRNA / lncRNA / retrotransposons / oocyte-to-embryo transition / genome activation

Subject area(s): Development | Genomic & Computational Biology | RNA