
Synthetic biology of minimal systems
Our ambition is to quantitatively understand fundamental phenomena in living systems on the scale of individually active molecules. Although our methods are tailored to investigate single molecules in living cells and embryos, we found that for a better understanding from first principles, it is indispensable to also reconstitute selected subsystems, which we explore in the framework of bottom-up synthetic biology.
Keywords
Single molecule biophysics / model membranes / synthetic biology / microfluidics