EMBO Member
Philip Cohen
EMBO 1982
University, Dundee, United Kingdom
Regulation of the innate immune system
The major aim of my laboratory is to dissect the signal transduction networks that control the production of inflammatory mediators during infection by bacteria and viruses and to understand how the deregulation of these pathways leads to inflammatory and autoimmune diseases. I am particularly interested in the interplay between phosphorylation and ubiquitylation in regulating innate immune signaling networks.
Keywords
Protein phosphorylation / pro-inflammatory cytokines / protein kinases / signal transduction / ubiquitylation