EMBO Member
Institut de Génétique Humaine, Montpellier | France
EMBO 2024
My lab investigates the origin and the consequences of replication stress in yeast and human cells using a combination of single-molecule imaging and genome-wide approaches. Our main research interests include transcription-replication conflicts and R-loops, fork remodeling by SMC complexes, checkpoint signaling, and activation of the innate immune response by cytosolic DNA released from stressed replication forks.
Keywords: Replication stress / R-loops / transcription-replication conflicts / SMC complexes / genomic instability / checkpoints / inflammation / cancer
Subject area(s): Cell Cycle | Genome Stability & Dynamics | Genomic & Computational Biology