Recognition and regulation of mammalian proteins
My research group studies the molecular mechanisms of recognition and regulation that underlie biomedical important processes. Our major expertise is in protein crystallography and its application to large multi-domain human plasma proteins and cell-surface receptors. We focus on key steps in the human immune defense by the complement system and, recently, adult stem cell differentiation and proliferation.
Keywords
Protein crystallography / complement system / plasma proteins / membrane proteins / mammalian protein expression