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EMBO Member

Ralf Adams

MPI für Molekulare Biomedizin, Münster | Germany

EMBO 2014

Molecular regulation of angiogenesis

Our research is mainly concerned with the development of the vascular system and relies strongly on inducible and tissue-specific genetic approaches in the mouse. Our work has provided insight into key processes controlling developmental blood vessel growth and, in particular, its regulation by Notch, VEGF and Eph/ephrin signaling. The specialization of blood vessels and vascular cells in different organs is another focus of our research.

Keywords: Cardiovascular / angiogenesis / endothelial cells / pericytes / mouse genetics / Eph / ephrin / Notch

Subject area(s): Cell & Tissue Architecture | Development | Signal Transduction