
EMBO Member
Ralf Adams
EMBO 2014
Former EMBO Young Investigator (2001)
Molecular regulation of angiogenesis
Our research is mainly concerned with the development of the vascular system and relies strongly on inducible and tissue-specific genetic approaches in the mouse. Our work has provided insight into key processes controlling developmental blood vessel growth and, in particular, its regulation by Notch, VEGF and Eph/ephrin signaling. The specialization of blood vessels and vascular cells in different organs is another focus of our research.
Keywords
Cardiovascular / angiogenesis / endothelial cells / pericytes / mouse genetics / Eph / ephrin / Notch