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EMBO Member

Raymond A. Dwek

University of Oxford | United Kingdom

EMBO 1988

Iminosugars as broad spectrum antivirals

Iminosugars, which can interfere with cellular glycosylation pathways, provide a route to affect glycan-mediated virion assembly. Iminosugars offer an exciting prospect for the development of broad-spectrum antivirals against enveloped viruses. Our lab is currently involved in clinical trials for dengue virus.

Keywords: Glycobiology / immunology / virology / structure & function of oligosaccharides / antiviral iminosugars

Subject area(s): Immunology | Microbiology, Virology & Pathogens | Proteins & Biochemistry