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EMBO Member

Reuven Agami

Netherlands Cancer Institute, Amsterdam | Netherlands

EMBO 2007

Uncovering novel vulnerabilities of cancer

Our main research objective is to identify novel cellular vulnerabilities that can be exploited for cancer therapies. We develop innovative genomic and genetic tools. Key targets are non-coding RNAs, mRNA translation, and enhancers. We employ functional genetic screening approaches, perform mechanistic studies, and use this information for the development of innovative cancer therapeutic approaches.

Keywords: Functional genetic tools / cancer / tumor suppressor / enhancer / mRNA processing / RNA binding proteins / protein translation / amino acid metabolism

Subject area(s): Cell Cycle | Genomic & Computational Biology | RNA