EMBO Member
Reuven Agami
EMBO 2007
Former EMBO Young Investigator (2005)
Netherlands Cancer Institute, Amsterdam, Netherlands
Uncovering novel vulnerabilities of cancer
Our main research objective is to identify novel cellular vulnerabilities that can be exploited for cancer therapies. We develop innovative genomic and genetic tools. Key targets are non-coding RNAs, mRNA translation, and enhancers. We employ functional genetic screening approaches, perform mechanistic studies, and use this information for the development of innovative cancer therapeutic approaches.
Keywords
Functional genetic tools / cancer / tumor suppressor / enhancer / mRNA processing / RNA binding proteins / protein translation / amino acid metabolism