Netherlands Cancer Institute, Amsterdam | Netherlands
Our main research objective is to identify novel cellular vulnerabilities that can be exploited for cancer therapies. We develop innovative genomic and genetic tools. Key targets are non-coding RNAs, mRNA translation, and enhancers. We employ functional genetic screening approaches, perform mechanistic studies, and use this information for the development of innovative cancer therapeutic approaches.
Keywords: Functional genetic tools / cancer / tumor suppressor / enhancer / mRNA processing / RNA binding proteins / protein translation / amino acid metabolism