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EMBO Member

Richard A. Flavell

Yale University School of Medicine, New Haven | United States

EMBO 1978 | Council 82–83

Adaptive and innate immunity

My laboratory uses mouse reverse genetics to study innate and adaptive immunity, T cell tolerance, apoptosis and autoimmunity, and the regulation of T cell differentiation. For the past 8 years, we have been developing and improving a humanized mouse model capable of supporting engrafted human hematopoietic stem cells and allow the generation of both adaptive and innate immune effector cells.

Keywords: Molecular regulation of the immune response

Subject area(s): Immunology | Molecular Medicine | Signal Transduction