Yale University School of Medicine, New Haven | United States
EMBO 1978 | Council 82–83
My laboratory uses mouse reverse genetics to study innate and adaptive immunity, T cell tolerance, apoptosis and autoimmunity, and the regulation of T cell differentiation. For the past 8 years, we have been developing and improving a humanized mouse model capable of supporting engrafted human hematopoietic stem cells and allow the generation of both adaptive and innate immune effector cells.
Keywords: Molecular regulation of the immune response
Subject area(s): Immunology | Molecular Medicine | Signal Transduction