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Portrait of Richard J. Jackson

EMBO Member

Richard J. Jackson

Deceased

EMBO 1991

1940 – 2020

The mechanism of mammalian translation initiation

In recent years our research has focussed on the following three topics: (i) the mechanism of the reinitiation that occurs following translation of a short upstream ORF in higher eukaryotes; (ii) the mechanism of initiation site selection on different sub-classes of picornavirus IRESs; and (iii) the mechanism of stimulation of picornavirus IRESs by polypyrimidine tract binding protein.

Keywords

Mammalian mRNA translation / initiation mechanisms / viral IRESs / translational control / microRNAs

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