Cancer Research UK Manchester Institute, Manchester | United Kingdom
We study the molecular mechanisms underlying melanomagenesis, with particular emphasis on the role of the RAS/RAF/MEK/ERK pathway. We employ biochemistry, molecular biology, cell biology, structural biology, transgenic models and genetics. A key aim is to translate our basic findings into clinical practice.
Keywords: Cell signalling / BRAF & RAS / melanoma / transgenic models / translational research