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EMBO Member

Rickard Sandberg

Karolinska Institutet, Stockholm | Sweden

EMBO 2019

Single-cell genomics to decipher gene regulation

My group focuses on using single-cell genomics to better understand the regulation of gene expression and transcriptional dynamics in mammalian cells, with recent focus on allelic expression and transcriptional burst kinetics. The long-term aim is to decipher the regulatory logic within enhancer and promoter sequences to infer cell and development-stage specific gene expression that can interpret genetic variation and enable synthetic biology.

Keywords: Single-cell genomics / transcription / computational biology / development / RNA

Subject area(s): Genomic & Computational Biology | RNA | Development | Chromatin & Transcription

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