Regulatory networks patterning vertebrate development
Our lab uses developmental genetics in vertebrate model systems to understand how transcriptional regulatory networks control the formation and patterning of the body plan and organs during mammalian development; how they are associated with or affected in disease; and the role of these pathways in vertebrate evolution. A molecular focus is on the regulation and role of Hox genes.
Keywords
Neural development / homeobox genes / transcriptional regulation / pattern formation / craniofacial development / neural crest / gene regulatory networks / evolution