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EMBO Member

Robert J. Klose

University of Oxford | United Kingdom

EMBO 2021

Epigenetic control of gene expression

In my group we strive to understand how gene expression is controlled by chromatin-based and epigenetic systems, with a focus on CpG island elements in vertebrates. We use a multidisciplinary approach leveraging biochemistry, molecular genetics, genomics, and live-cell imaging to achieve this. With this new understanding, we aspire to then discover how these systems lead to human diseases when perturbed.

Keywords: CpG Islands / chromatin / epigenetics / gene regulation & transcription

Subject area(s): Chromatin & Transcription | Proteins & Biochemistry