Stanford University School of Medicine | United States
We are interested in understanding how intercellular signals control embryogenesis and organogenesis. Molecules of the Wnt family regulate numerous decisions that cells make during embryogenesis. Wnt signals also influence how stem cells divide. Unrestrained Wnt signaling, after mutations in Wnt signaling components, is implicated in cancer. Currently, my research focuses on how Wnt sigals influence stem cell self-renewal.
Keywords: Oncogenes / Wnt genes / stem cells / signaling / cancer
Subject area(s): Cell & Tissue Architecture | Development | Signal Transduction