Philipps-Universität, Marburg | Germany
My group is interested in the biogenesis and function of cellular iron-sulfur proteins. We try to understand how eukaryotic cells assemble iron-sulfur clusters and insert them into target apoproteins. Our research also focusses on the molecular basis of diseases associated with genetic defects in iron-sulfur protein biogenesis, and on tightly associated processes such as cellular iron regulation and the maintenance of genome integrity.
Keywords: Iron-sulfur proteins / mitochondrial function & diseases / post-translational modifications / iron & sulfur metabolism / ABC transporters / metal biology / electron transfer reactions / spectroscopy
Subject area(s): Cellular Metabolism | Membranes & Transport | Proteins & Biochemistry